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LifeVantage Research Evaluates Benefits of Protandim Nrf2 on Oxidative Stress

BY DSN Staff Writer | October 30, 2026 | read / Daily News

LifeVantage Corporation completed an in vitro research study examining the effects of modern environmental toxins, like pollution, microplastics, hormone disruptors and pesticides, on cellular health and the role Protandim Nrf2 can play in helping defend against their impact.

The study evaluated the protective benefits of Protandim Nrf2 against oxidate stress in the body and assessed three cell types from the liver (HepG2), skin and connective tissue (Fibroblasts) and intestinal lining (Caco-2).

“Modern life exposes people to things they cannot always see or avoid,” said Terrence Moorehead, LifeVantage CEO. “Our work begins with a powerful belief: the body has remarkable systems designed to defend itself. This research advances our understanding of how Protandim Nrf2 can support those natural capabilities so people can continue living fully.”

Using fluorescent imaging to make oxidative stress visible, the researchers assessed cell viability and found that all five tested environmental toxins adversely affected the cells. Those exposed to the toxins and then Protandim Nrf2, however, showed significantly lower oxidative stress signals. In some cases, the study reported, the stress signals returned to levels comparable to those in unexposed cells.

“When people hear ‘oxidative stress’ or ‘environmental toxins,’ they often picture something far removed from their own lives like industrial factories or farming equipment,” said Lisa Barnes, LifeVantage Vice President of Research and Development. “We wanted to study exposures that feel familiar and modern: the air around us, the foods we eat and the products we use. What excites me about these findings is the possibility of empowering the human body to meet those everyday challenges by activating the powerful defenses it already has within.”

LifeVantage reported that Protandim Nrf2 reduced a marker of oxidative stress by an average of 40% after 30 days. With these new findings, the company launched Cell Care, a campaign designed to make cellular health more personal, visible and easy to understand.

“Cell Care turns complex science into a simple, personal question: What is your everyday routine asking of your cells?” said Wendy Freedman, LifeVantage Vice President of Global Marketing. “The quiz helps people recognize exposures they may never have considered and gives them an easy way to start a conversation about supporting their bodies from within. Ultimately, it is about helping people make proactive choices and live healthier, longer.”

Posted in Daily News and tagged LifeVantage, research, Terrence Moorehead, Wendy Freedman.
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