Founded | 1998
Headquarters | Utah
Top Executives | David Lisonbee / Founder & Danny Lee / President & CEO
Product Category | Health & Wellness
The immune system is an intricate network designed to strengthen and protect. For more than 25 years, 4Life has made that the focus of their customer-centric mission. Widely recognized as The Immune System Company, its roots in science-based wellness products and a strong commitment to community empowerment, 4Life’s story is one of innovation, resilience and global impact.
A Powerful Legacy
Founded in 1998 by David and the late Bianca Lisonbee, 4Life Research began with the revolutionary immune support product, Transfer Factor. Bianca’s inspiration for the product came after she discovered early research about transfer factors—molecules that help “educate” immune cells. The couple recognized the potential of this science to improve lives and launched 4Life with a mission to promote wellness and financial opportunity.
Bianca Lisonbee’s philanthropic vision extended beyond product innovation. In 2006, she founded Foundation 4Life, a nonprofit organization dedicated to alleviating childhood poverty and empowering vulnerable communities worldwide. Over its nearly 20-year history, the Foundation has implemented service projects in more than 20 countries, including disaster relief, literacy campaigns and partnerships with organizations such as SOS Children’s Villages. Tragically, Bianca passed away in 2023, but her legacy lives on through the Foundation’s work under the leadership of her daughter, Jenna Lisonbee.
Science-First Solutions
4Life’s product line centers on immune support and wellness, with Transfer Factor as its flagship offering. “We are a science-first, product-first company,” shared Calvin Jolley, Vice President, Corporate Communications. The products are “messenger molecules” that transfer immune system memory and knowledge from one entity to another. Today, more than 50 products contain Transfer Factor, giving independent affiliates more ways to connect with customers and meet their health needs.
Customers are drawn to the brand for its commitment to innovation and quality, often forming strong relationships with 4Life’s products before transitioning to become affiliates. The company’s research-driven approach has led to a diverse product portfolio, including targeted nutritional supplements, protein powders and skincare solutions—all with a 100 percent satisfaction guarantee.
This dedication to science ensures that every product not only meets customer needs but also aligns with the company’s values of improving lives worldwide. One of the company’s key goals is to get Transfer Factor in three million homes by 2030.
Latin American Roots
A defining feature of 4Life’s growth is its deep connection with the Latin American market. The company’s first major leaders emerged in Puerto Rico and quickly expanded throughout the Spanish-speaking world. Today, Latin America remains a core focus, with Spanish serving as the company’s first operational language.
“The Latin American market has been crucial to our success,” says Founder David Lisonbee. “When a company establishes a Latin leader in the field, learn how to listen. What you think you know about the US market is quickly readjusted. Latin consumers look for different options, in products and opportunities. Ours is not a one-size-fits-all market. You must be able to segment and diversify. You must be able to appeal to this culturally unique demographic.”
Calvin says the company has always grown organically. Today, many of the top affiliates are from Puerto Rico, Mexico, Colombia, throughout South America and—of course—from coast-to-coast in the USA.
“Our largest segment is the first- and second-generation Latino market in the United States, particularly on the coasts.” This continued growth is testament to the strong leadership within the Latin American community and their ability to bring the 4Life opportunity back to the US.
Sales Force and Community Impact
At the heart of 4Life’s success is its dedicated network of affiliates. The sales force’s organic growth was built through genuine relationships rather than recruitment incentives. “People come to us as customers, and they continue their journey—if they choose to—as affiliates,” explained Danny Lee, 4Life President and CEO.
This focus fosters a strong sense of community among affiliates and customers, united by a shared belief in the product and the company’s mission. The emphasis on service, both through Foundation 4Life and local community projects, creates brand loyalty. 4Life Fortify, for example, is a nutrition program to provide children and their families with the necessary tools to become self-sufficient and discover the power to break the cycle of poverty for generations. Every purchase of 4Life Fortify is donated to Feed the Children, who then distributes the meals.
In-House Technology
As the direct selling landscape evolves, 4Life continues to leverage technology to enhance its operations and reach. From its state-of-the-art research and development facilities to the use of digital tools for affiliate training and marketing, 4Life demonstrates a commitment to staying at the forefront of industry innovation.
Nothing is off the shelf. The company built its mobile app in-house, and the affiliates’ replicated websites feature level-specific training modules and a health questionnaire for customers to answer. This helps create a targeted, personal approach to optimize their wellness with the products. Through the shop feature in the app, affiliates can share a link with anyone anywhere in the world—and immediately apply a discount to their purchase.
We have a really robust social media presence,” Calvin shared. “And everything that you expect from an IT-savvy contemporary company. We are constantly talking to our affiliates, so we know what they need. We’re on the first line in terms of what they want to best operate their business.”
4Life’s story is a powerful example of what can be achieved when science, service and community come together. The company’s unwavering dedication to improving lives through innovative products and global philanthropy has established it as a leader in both wellness and direct selling. With its roots firmly planted in the vision of its founders and its eyes set on the future, 4Life continues to inspire and empower individuals worldwide.
From the January/February 2025 issue of Direct Selling News magazine.
